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Sanum
SANUM Pharmaceuticals, The PLEO™ SAN Sanukehl Preparations Polysaccharides for Haptenic Therapy

(This is the first in a new series of articles on PLEO™ SAN (Sanukehl Hapten) preparations in Explore! for the Professional.)

(Explore Issue: Volume 10, Number 1)

Introduction

For many diseases, a pathogen's toxins can still be present after the germ itself has been eliminated, thus perpetuating the disease. In fact, the toxins might be the sole disease-causing agent. To protect themselves from their own toxins, pathogens produce specific polysaccharides (termed antigen absorbers by CORNELIUS) designed to bind the pathogen's own toxins or antigens, preventing them from becoming active. Moreover, viruses, bacteria, plants and animals know how to store and communicate information with the aid of saccharides. The code laid down in this language is thus able to influence a multitude of regulatory processes in the host organism.

Furthermore, the low-molecular-weight polysaccharides represent haptens, which -- when coupled to a higher-molecular-weight carrier (e.g., protein) -- can stimulate cellular and humoral defenses. Bacterial toxins released during earlier infections and not eliminated from the body due to immune-system deficiencies can be bound by haptens, and thus represent an antigen. This antigen is capable of stimulating the immune system by activating the T lymphocytes, ultimately leading to elimination of the bacterial toxins.

Production of PLEO™ SANS

The initial materials for the various PLEO™ SANS are dead cells of the corresponding bacterial or fungal types. Using a painstaking extraction process, the polysaccharides necessary for haptenic therapy are dissolved out of the organism's cell walls. Due to differences in the fine structure of these polysaccharides in each bacterial or fungal type, this results in a large number of antigen variations.

In the extractions process, the polysaccharides are separated out from undesired proteins, as well as from lipid A, which is also a cell-wall component in gram-negative bacteria. The proteins could trigger an allergic reaction, while lipid A is responsible for the toxic effect of the lipopolysaccharides (endotoxins) of gram-negative bacteria.

Polysaccharides from microorganisms are nontoxic to the host organism. For haptenic therapy with PLEO™ SANS, the extracted polysaccharide extract is homeopathically potentiated; the end result is largely free of proteins and endotoxins. Therefore, allergic and fever reactions due to the use of PLEO™ SANS are unlikely.

 

The following haptens are available as PLEO™ SAN Preparations in homeopathic dilutions:

Name   Source
PLEO™ SAN ACNE Propionibacterium acnes, 5X Drops, 5X Sips
PLEO™ SAN BRUCEL Brucella melitensis, 6X Drops, 6X Sips
PLEO™ SAN CAND Candida albicans, 6X Drops, 5X Sips
PLEO™ SAN COLI Escherichia coli, 6X Drops, 7X Sips
PLEO™ SAN KLEBS Klebsiella pneumoniae, 6X Drops, 6X Sips
PLEO™ SAN MYC Mycobacterium bovis (BCG), 6X Drops, 5X Sips
PLEO™ SAN PROT Proteus vulgaris, 6X Drops, 7X Sips
PLEO™ SAN PSEU Pseudomonas aeruginosa, 6X Drops, 5X Sips
PLEO™ SAN SALM Salmonella enteriditis, 6X Drops, 6X Sips
PLEO™ SAN STAPH Staphylococcus aureus, 6X Drops, 5X Sips
PLEO™ SAN STREP Streptococcus pyogenes, 6X Drops, 5X Sips
PLEO™ SAN TRICH Trichophyton verrucosum, 6X Drops, 5X Sips

Using PLEO™ SANS

Because of their effect in the organism, the PLEO™ SAN Preparations are utilized in the following areas:

1. Specific Terrain Cleansing

Specific terrain cleansing of microorganisms or their metabolic products is possible with the aid of the PLEO™ SAN Preparations in conjunction with microbiological or mycological findings. In addition, the corresponding PLEO™ SANS should be used against infections with similar pathogens.

Administering specific polysaccharides communicates specific information to the host organism, which it needs to regulate its symbiontic equilibrium with the microorganisms in question.

2. Stimulating the Immune System and Eliminating Reaction Blockages

After binding to a carrier molecule in the organism, haptens can trigger a humoral as well as a cellular immune response. These mechanisms neutralize and eliminate microbial antigens. Introducing the PLEO™ SAN structures to the body very quickly leads to immune-complex formation using the immunoglobulins present. This substance presumably functions as an immune modulator which effects a correction of immune-regulatory imbalances and develops its effect, for example, via induction of cytokines, particularly GM-CSF and IL-10. Based on investigations into the effects of PLEO™ SAN Pseu, it was possible to derive, in an immunologically substantiatable manner, that long-lasting reaction blockages (e.g. as a consequence of treatment with corticosteroids) in cancer patients, or in cases of immune-system suppression, can be eliminated with the aid of the stimulating effect of SANUM Pharmaceuticals.

3. Hyposensitization

Haptens can also bind the antibodies or circulating immune complexes created to counteract the corresponding complete antigen. These antibodies (IgG) exhibit a blocking activity to allergic reactions that is transmitted by another antibody class (IgE). As hyposensitization continues to develop, the proportion of IgG often increases, while the concentration of IgE in the blood serum falls off.

4. Intermediate Agents when Treating with Nosodes

This effect is based on the absorption of the pathogenic antigens or toxins. Severe initial deterioration or antigen blockages are alleviated or eliminated by PLEO™ SAN Preparations.

5. As a Pharmaceutical for Individual Clinical Indication
(see also the Materia Medica, page 201)

Usage (Drops)Take: for acute conditions, 5 - 10 drops every 12 - 24 hours; for chronic illnesses, 10 drops every other day.

As an embrocation: 5 - 10 drops every 1 or 2 days at the site of the disease or in the bend of the elbow. After 8 months, therapy should be discontinued for several months.

Usage (sips) 1 ml SC 1 - 3 times per week

Side EffectsThe presence of certain specific organic components can, in rare cases, trigger hypersensitivity reactions.

PLEO™ SAN Acne® Drops 5x

Active agent: Propionibacterium acnes
Nosode:
Corynebacterium acnes
Naturopathically documented areas of application:
Acne conglobata, rheumatoid arthritis
Also available in sips 5x

PLEO™ SAN Brucel® Drops 6x

Active agent: Brucella melitensis
Nosode:
Brucella abortus
Naturopathically documented areas of application:
Myalgia, subacute rheumatoid arthritis, intermittent fever
Also available in sips 6x

PLEO™ SAN Cand® Drops 6x

Active agent: Candida albicans
Nosode:
Monilia albicans
Naturopathically documented areas of application:
Oral diseases (stomatitis, gingivitis, perlèche, aphthous ulcers), spasmodic painful small intestine, colitis, constipation after treatment with antibiotics, allergic asthma, inflammation of the vulva, vulvovaginitis, Crurosis vulvae, rectilinear fissural skinfold or mucous-membrane eczema, interdigital eczema of the hands or feet, dermatosis after treatment with antibiotics
Also available in sips 5x

 

PLEO™ SAN Coli® Drops 6x

Active agent: Escherichia coli
Nosode:
Bac. coli
Naturopathically documented areas of application:
Cholangitis, cholecystitis, gastroenteritis, colitis, pyelonephritis, spermatocystitis, epididymitis, cystitis, prostatitis, salpingitis, metritis, vaginitis
Also available in sips 5x

PLEO™ SANKlebs® Drops 6x

Active agent: Klebsiella pneumoniae
Nosode:
--
Naturopathically documented areas of application:
For supportive therapy during or after Friedländer's pneumonia; in cases of silicosis, pneumoconiosis, bronchiectasis, bronchial asthma; as an adjuvant in cases of acute influenza, pleuritis, pneumonia; for therapeutic injury after antibiotic therapy
Also available in sips 7x

PLEO™ SAN Myc® Drops 6x

Active agent: Mycobacterium bovis
Nosode:
Tuberculinum bovis
Naturopathically documented areas of application:
Aphonia, bronchial asthma, cardiac arrhythmia, arthritis, juvenile acne, cholecystitis, cystopyelitis, eczema with fissures, enterocolitis, hordeolum, hydrocele, conjunctivitis, keratitis, headaches, laryngeal ulcer, cardialgia, Lupus erythematodes, metritis, nephritis, otitis, osteochondrosis, pleuritis, psoriasis, rhinitis, ventricular or duodenal ulcers, urticaria
Also available in sips 5x

PLEO™ SAN Prot® Drops 6x

Active agent: Proteus vulgaris
Nosode:
Bac. proteus
Naturopathically documented areas of application:
Gastroenteritis, peritonitis, cystopyelitis, puerperal sepsis, otitis, gangrenous pulmonary processes, osteomyelitis, abnormal intestinal bacterial flora after antibiotic therapy, peripheral circulatory disorders, ventricular or duodenal ulcers, hematemesis, angio-neurotic edema, Menière's disease, herpes
Also available in sips 7x

PLEO™ SAN Pseu® Drops 6x

Active agent: Pseudomonas aeruginosa
Nosode:
Bac. pyocyaneus
Naturopathically documented areas of application:
Infectious and allergic dermatitis, pruritus, insect bites, angioneurotic edema, collagen disease, arthropathic fibrositis, keloids, Ulcus cruris, burns, bronchial asthma, otitis, sinusitis, pharyngitis, chronic bronchitis, hay fever
Also available in sips 5x

PLEO™ SAN Salm® Drops 6x

Active agent: Salmonella enteriditis
Nosode:
Bac. gärtner
Naturopathically documented areas of application:
Growth inhibition, chronic pancreatitis, enterobiasis (oxyuriasis), chronic gastroenteritis, celiac disease, furunculosis, rheumatic fever
Also available in sips 5x

PLEO™ SAN Staph® Drops 6x

Active agent: Staphylococcus aureus
Nosode:
Staphylococcus aureus
Naturopathically documented areas of application:
Folliculosis, furunculitis, impetigo, blepharitis, hordeolum, tarsal cyst, angina, otitis, sinusitis, mastoiditis, meningitis, osteomyelitis, nephritis, urogenital staphylococcal infections
Also available in sips 5x

PLEO™ SAN Strep® Drops 6x

Active agent: Streptococcus pyogenes
Nosode:
Streptococcinum
Naturopathically documented areas of application:
Alopecia, Angina tonsillaris, cardialgia, eczema, endocarditis, myocarditis, pericarditis, empyema, puerperal mastitis, migraine, osteomyelitis, Otitis media, phlegmon, chronic rheumatoid arthritis
Also available in sips 5x

PLEO™ SAN Trich® Drops 6x

Active agent: Trichophyton verrucosum
Nosode:
Trichophytosis
Naturopathically documented areas of application:
Mycoses of the hairs, skin, nails; tinea, trichophytosis
Also available in sips 5x

 

Bibliography

Cornelius, P. (1990): Nosoden und Begleittherapie [Nosodes and Adjuvant Therapy]. Pflaum Verlag, Munich.

Hartmann, J. (1998): Das Sanum-Präparat PLEO™ SAN Brucel [The Sanum Preparation PLEO™ SAN Brucel]. Sanum-Post 42 (in press).

Krämer, S. (1997): "Leukozytopenie" [Leukocytopenia]. Gesundes Leben [Living Healthy] 4:70.

Kunze, R. and J. Hartmann (1997): "Das immunologische Profil von PLEO™ SAN Pseu" [The Immunological Profile of PLEO™ SAN Pseu]. Erfahrungsheilkunde [Empirical Medicine] 3:181 - 88.

Kunze, R. and J. Hartmann (1997): "Aufhebung hydrocortisonbedingter Immunsuppression" [Elimination of Hydrocortisone-Induced Immune Suppression]. Sanum-Post 41:2 - 6

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