Immunostimulation by Bacillus Subtilis Preparations

© Copyright 2003 by J. Hartmann, B. Sci/Biology, Production Manager, SANUM-Kehlbeck; Germany
(Explore Issue: Volume 12, Number 1)

Considering chronic, persisting infections with resistant infective agents as well as immunocompromised patients, the utilization of classic antibiotics and chemotherapeutics reaches its limits.

Unspecific activators of the immumologic system, derived from the knowledge of folk medicine, are now administered more intensively in apparently therapy-resistant diseases.

Bacillus subtilus as whole cells, spores and cell wall fractions is comparable to or even superior to the patent herbal immunostimulant Echinacea purpurea considering its efficacy.

Classic in-vitro and in-vitro tests for immunstimulation as the granulocyte-smear-method, the carbon-clearance-test, the chemiluminescence-model and the T-lymphocyte-test document the enhancement of the body's unspecific acting defense mechanism.

Recent clinical trials confirm efficacy of Bacillus subtilus in the treatment of chronic recidiving infections of the urinary tract, the respiratory tract of patients with defects and with food allergies.

The actual concept immunostimulation - or more correct - of immunomodulation began its development starting from the experiences for example with the Bier's iodine drops for arresting of cold or with injections of blood proteins and lactalbumin for the treatment of inflammations by Ferdinand Hoff. From this therapeutica1 attempt stems the knowledge of the disturbed defensive power of the body as the basis for chronical infectious diseases.