The Klinghardt Neurotoxin Elimination Protocol

© Copyright 2002 by Dietrich Klinghardt M.D., Ph.D., USA.
(Explore Issue: Volume 12, Number 2)

Approved by:
American Academy of Neural Therapy and
Institute of Neurobiology (Bellevue, WA, USA)
Institute for Neurobiologie (Stuttgart, Germany)
Academy for Balanced NeuroBiology Ltd (London, United Kingdom)

This lecture was presented by Dietrich Klinghardt M.D., Ph.D. at the Jean Piaget Department at the University of Geneva, Switzerland Oct. 2002 to physicians and dentists from Europe, Israel, several Arab countries and Asia

Introduction:
What are Neurotoxins?

Neurotoxins are substances attracted to the mammalian nervous system. They are absorbed by nerve endings and travel inside the neuron to the cell body. On their way they distrupt vital functions of the nerve cell, such as axonal transport of nutrients, mitochondrial respiration and proper DNAtranscription. The body is constantly trying to eliminate neurotoxins via the available exit routes: the liver, kidney, skin and exhaled air. Detox mechanisms include acetylation, sulfation, glucuronidation, oxidation and others. The liver is most important in these processes. Here most elimination products are expelled with the bile into the small intestine and should leave the body via the digestive tract. However, because of the lipophilic/neurotropic nature of the neurotoxins, most are reabsorbed by the abundant nerve endings of the enteric nervous system (ENS) in the intestinal wall. The ENS has more neurons than the spinal chord. From the moment of mucosal uptake the toxins can potentially take 4 different paths:

1. neuronal uptake and via axonal transport to the spinal chord (sympathetic neurons) or brainstem (parasympathetics) – from here back to the brain.
2. Venous uptake and via the portal vein back to the liver
3. Lymphatic uptake and via the thoracic duct to the subclavian vein
4. Uptake by bowel bacteria and tissues of the intestinal tract
   Here is an incomplete list of common neurotoxins in order of importance:

(i) Heavy metals: such as mercury, lead, cadmium and aluminium.

(ii) Biotoxins: such as tetanus toxin, botulinum toxin (botox), ascaridin (from intestinal parasites), unspecified toxins from streptococci, staphylococci, lyme disease, clamydia, tuberculosis, fungal toxins and toxins produced by viruses. Biotoxins are minute molecules (200-1000 kilodaltons) containing nitrogen and sulfur. They belong to a group of chemical messengers which microorganisms use to control the host´s immune system, host behaviour and the host´s eating habits.

(iii) Xenobiotics (man-made environmental toxins): such as dioxin, formaldehyde, insecticides, wood preservatives, PCBs etc.

(iv) Food Preservatives, excitotoxins and cosmetics: such as aspartame (diet sweeteners) food colourings, flouride, methyl-and propyl-paraben, etc.

I have found that mercury in its different chemical forms has a synergistic amplifying effect with all other neurotoxins. When mercury is removed, the body starts to more effectively eliminate all other neurotoxins, even if they are not adressed.