Mechanism of Possible Biological Effect of Activated Water on Patients Suffering from Alzheimer’s Disease

© Copyright 2003 by Dr. Igor V. Smirnov, Ph.D. and M.S., USA
(Explore Issue: Volume 12, Number 5)

In Alzheimer’s disease, there is an overall shrinkage of brain tissue. In addition, the ventricles or chambers within the brain that contain cerebrospinal fluid are noticeably enlarged. In the early stages of Alzheimer’s disease, short-term memory begins to decline when the cells in the hippocampus, which is part of the limbic system, degenerate. The ability to perform routine tasks also decline. As Alzheimer’s disease spreads through the cerebral cortex (the outer layer of the brain), judgment declines, and emotional outburst may occur, and language is impaired. Progression of the disease leads to the death of more nerve cells and subsequent behavior changes, such as wandering and agitation. The ability to recognize faces and to communicate is completely lost in the final stage. The stage of complete dependency of patient may last for years before he dies. The average length of time from diagnosis to death is 4 to 8 years, although it can take 20 years or more for the disease to run its course.

One of the hallmarks of Alzheimer’s disease is the accumulation of amyloid plaques between nerve cells (neurons) in the brain. Amyloid is a general term for protein fragments the body produces on a regular basis. Beta-amyloid is a fragment of a protein that is snipped from another protein called amyloid precursor protein. In a healthy brain, these protein fragments would be broken down and eliminated. In the case of Alzheimer’s disease, the fragments accumulate to form hard, insoluble plaques.

Another factor that leads to development of Alzheimer’s disease is formation of abnormal neurofibrillary tangles in neurons. These primarily consist of a protein called tau, which forms part of a structure called a microtubule. The microtubule helps transport nutrients and other important substances from one part of the nerve cell to another. In the case of Alzheimer’s disease, however, the tau protein is abnormal and the microtubule structures are collapsed.
Activated water is a liquid substance with pre-recorded molecular activities, that supports sophisticated mechanism required commanding the extraordinary complex and rapid cascade of intricate biochemical reactions in the body. A number of biological tests, including tests in vitro on cellular cultures and in vivo on plants, provide some evidence that the molecular structure of Activated water resembles the structure of biowater found in biological systems.

The latest research show that transitions in cytoplasm of the neuron’s body, produced by collective disassembling of big number of filaments and microtubules, as a consequence of nerve excitation and neuron’s body depolarization, are generated by quantum transitions of the coherent water clusters, localized in cytoplasm and in the microtubules of neurons. As a result of coherent water clusters transitions in the neuron’s cytoplasm induced by reversible osmotic equilibrium, the distribution of synaptic contacts on the surface of cells, and ionic channels activity is changed. Thus it can provide generation of strong nerve impulses propagating via axons, excite big numbers of other neighboring nerve cells, and stimulate the learning process associated with long-term and short-term memory formation, since these processes are related to synaptic contacts reorganization in the brain. These changes create the long-term and short-term memory formation in the brain. The volume and shape pulsation of electrical signals in neurons and dendrites that control production of neurotransmitters occurs due to reversible change of the intracellular water activity, and corresponding passive osmotic diffusion of biowater from the external space around neurons. Therefore, the plentiful supply of biowater is very important for the support of the normal function of neurons in the brain. The ingestion of Activated water with molecular structure similar to biowater may prevent the dehydration of the brain tissue, and as a result eliminate the symptoms of neurological disorders.